Is there a place to rent a car in downtown Cincinnati?

Besides the Enterprise already mentioned, there is a Budget/Avis location on West Fourth Street. Budget tends to be less expensive than Avis, but Avis typically tends to offer frequent flyer miles points. Budget offers free pick-up service. The office, which contains both the Avis and Budget is open 7 days a week, something not typical in all cities as many urban rental offices are closed on Sundays. Sunday hours of operation are very short, so check ahead to make sure they fit into your plans.