What other New York City neighborhoods are similar to Garment District?

Shopping wise, SoHo. I agree with @JenMac. It is like the financial district and Midtown in a way.

Anywhere in midtown looks like the Garment District. It's all giant buildings, a lot of noise, a lot of people and a lot of trash. Midtown, in general, is the bane of most local's existence. I guess, architecturally, it's kind of like Financial District minus all of the historical landmarks. But, energy-wise, any part of midtown is kind of a nightmare.